How to make the mouse left handed in macOS 10.12 Sierra

Terminology:

‘Alt’ refers to the ‘Option’ key ( ⌥ )

If you have enabled ‘Use F1, F2, etc. keys as standard function keys’ under ‘Keyboard’ settings in ‘System Preferences’ then omit the ‘Fn’ key from the keyboard shortcuts shown in this article.

1. Open the ‘Apple Menu’ by clicking on the Apple icon () in the Menu Bar, or press ‘Fn’ +’Ctrl’ + ‘F2’ to highlight the Apple icon and press ‘Enter‘
2. Click to select ‘System Preferences…’ as shown in Fig 1 or press the down arrow key to highlight it and then press ‘Enter’.
   
   Fig 1
3. Click on the ‘Mouse’ icon or press ‘Tab’ repeatedly (you might need to press ‘Fn’ + ‘Ctrl’ + ‘F7’ first) to cycle through the icons until the ‘Mouse’ icon is highlighted with a blue border then press the ‘Spacebar’, see Fig 2.
   
   Fig 2
4. Under ‘Primary mouse button’ click the radio button next to ‘Right’ to make the right hand button on your mouse the primary button (there are no keyboard shortcuts to activate this), see Fig 3.
   
   Fig 3
5. When you are happy with your settings click the ‘Close’ (red) button at the top of the window or press ‘Cmd’ + ‘W’ to close the window.

Note: If this does not work it could be because your computer settings are managed by someone else (an IT department or administrator for example). If this is the case you will need to contact them to access these settings or for further help.